About Conolidine alkaloid for chronic pain
Most not too long ago, it's been determined that conolidine and the above derivatives act on the atypical chemokine receptor three (ACKR3. Expressed in related places as classical opioid receptors, it binds to a wide array of endogenous opioids. As opposed to most opioid receptors, this receptor acts like a scavenger and doesn't activate a next mes